By the end of this CME session, participants will be able to: 1. Understanding Puerperal Sepsis Define puerperal sepsis and describe its epidemiology and contribution to maternal morbidity and mortality. Explain the pathophysiology and common causative organisms associated with puerperal sepsis. 2. Risk Factors and Prevention Identify obstetric, medical, and health system–related risk factors for puerperal sepsis. Apply infection prevention and control measures during labour, delivery, and the postpartum period to reduce sepsis risk. 3. Early Recognition and Diagnosis Recognize early warning signs and symptoms of puerperal sepsis, including systemic inflammatory response and organ dysfunction. Utilize appropriate clinical assessment tools and investigations to support timely diagnosis. 4. Clinical Management Initiate prompt, evidence-based management including empiric antibiotic therapy, fluid resuscitation, and supportive care. Identify indications for escalation of care, referral, or surgical intervention for source control. Monitor response to treatment and manage complications effectively. 5. Multidisciplinary and Systems-Based Approach Coordinate care among obstetricians, midwives, nurses, anesthetists, laboratory staff, and critical care teams. Use case reviews, audits, and surveillance data to improve sepsis prevention and outcomes within maternity services.